Closed Solicitation · DEPARTMENT OF VETERANS AFFAIRS
AI Summary
The Department of Veterans Affairs seeks a contractor for preclinical toxicology and pharmacokinetic studies to support an experimental rheumatoid arthritis treatment. The work includes GLP compliant toxicity studies and pharmacokinetic assessments in adult rats, with a performance period from September 2026 to September 2027. This notice is for informational purposes only, and a formal solicitation will follow.
PRE SOLICITATION NOTICE Department of Veterans Affairs Network Contracting Office (NCO) 05 Title: A Joint Targeted Drug Delivery Approach for Arthritis Therapy Toxicity and Pharmacokinetics The Department of Veterans Affairs (VA), Network Contracting Office (NCO) 05, intends to issue a solicitation for preclinical toxicology and pharmacokinetic (PK) studies to support advancement of an experimental joint targeted liposomal delivery system for Rheumatoid Arthritis therapy. This requirement involves GLP compliant toxicity studies and GLP or non GLP PK studies in adult rats. The forthcoming solicitation will seek a contractor capable of performing: GLP single dose IV toxicity studies including clinical observations, weight/food intake monitoring, blood chemistry assessments, necropsy, and histopathology. GLP or non GLP pharmacokinetic studies including IV dosing, timed blood collection, plasma processing and storage, LC MS/MS analysis of dexamethasone and 6 hydroxydexamethasone, and calculation of PK parameters. A comprehensive final written report covering toxicity results, PK data, and analytical findings. Place of performance will be the contractor s laboratory. The anticipated period of performance is one year, approximately September 15, 2026 through September 14, 2027. This notice is issued solely for informational purposes. A formal solicitation and the Government s acquisition strategy will be issued after completion of market research. This notice does not constitute a solicitation and does not commit the Government to award a contract. Point of Contact: Robert O Keefe Jr., Contract Specialist Email: robert.okeefejr@va.gov
AJ13--PHARMARCOKINETICS FOR EXPERIMENTAL RHEUMATOID ARTHRITIS TREATMENT is a federal acquisition solicitation issued by DEPARTMENT OF VETERANS AFFAIRS. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.
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