Closed Solicitation · DEPARTMENT OF HEALTH AND HUMAN SERVICES

    SPRAGUE-DAWLEY RATS (CHARLES RIVER)

    Sol. FDA-130321Special NoticeROCKVILLE, MD
    Closed
    STATUS
    Closed
    closed Jul 18, 2025
    POSTED
    Jul 14, 2025
    Publication date
    NAICS CODE
    112930
    Primary industry classification
    PSC CODE
    8820
    Product & service classification

    AI Summary

    The Department of Health and Human Services, specifically the Food and Drug Administration, has issued a special notice regarding the sole source requirement for Sprague Dawley rats from Charles River Laboratories. These rats are essential for two specific protocols aimed at assessing the toxicity of tobacco-derived nicotine through repeated inhalation. The continuity of using this specific strain is crucial for valid scientific data and ongoing research, as any change in supplier would compromise the integrity of the studies.

    Contract details

    Solicitation No.
    FDA-130321
    Notice Type
    Special Notice
    Posted Date
    July 14, 2025
    Response Deadline
    July 18, 2025
    NAICS Code
    112930AI guide
    PSC / Class Code
    8820
    Primary Contact
    Suzanne Martella
    State
    MD
    ZIP Code
    20857

    Description

    See attached Notice of Intent to Sole Source requirement for Sprague Dawley rats for protocols: E07877.01 and E07876.01 to access the toxicity of tobacco derived nicotine after repeated inhalation. Both studies will provide robust scientific data that will be used to identify and assess potential public health concerns related to nicotine inhalation exposures. This acquisition is restricted to Charles River Laboratories as these same rats were provided by Charles River for the methods development for the aforementioned approved protocols and it is imperative the lab continues using this specific strain from Charles River to ensure all behavioral testing and scientific data interpretation can be compared in ongoing research. A change in strain and supplier would result in invalidation of the studies of which any initial efforts will essentially be uninformative, unpublishable, nor can the results be used to support regulatory activities.

    Key dates

    1. July 14, 2025Posted Date
    2. July 18, 2025Proposals / Responses Due

    Frequently asked questions

    SPRAGUE-DAWLEY RATS (CHARLES RIVER) is a federal acquisition solicitation issued by DEPARTMENT OF HEALTH AND HUMAN SERVICES. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.

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