Closed Solicitation · DEPARTMENT OF HEALTH AND HUMAN SERVICES
AI Summary
The National Institute of Environmental Health Sciences is planning to issue an RFP for support in evaluating and conducting computational and alternative toxicological methods. This acquisition aims to enhance toxicological testing without animal use, focusing on various health effects from chemical exposures. The contract will be a 100% Small Business Set-Aside, with a potential performance period of up to 10 years.
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences This Pre-Solicitation Announcement is issued by the NICHD Office of Acquisitions on behalf of the National Institute of Environmental Health Sciences (NIEHS). THIS IS NOT A REQUEST FOR PROPOSALS (RFP). THIS IS A PRE-SOLICITATION ANNOUNCEMENT ONLY. NO RESPONSES ARE DUE AT THIS TIME. A REQUEST FOR PROPOSALS (RFP) WILL BE ISSUED VIA SAM.GOV CONTRACT OPPORTUNITIES ON OR ABOUT SEPTEMBER 17, 2025. The National Institute of Environmental Health Sciences (NIEHS) is planning to issue an RFP for a follow-on contract for Support for Evaluating and Conducting Computational and Alternative Toxicological Methods. The acquisition will support and assist the National Institute of Environmental Health Sciences (NIEHS) by conducting and evaluating toxicological testing using computational and/or alternative approaches, also referred to New Approach Methodologies (NAMs). NAMs broadly refers to any technology, methodology, approach, and/or combination of the three that can provide information on chemical hazard and risk assessment without the use of animals, such as in silico, in chemico, in vitro, and ex vivo approaches. The areas of focus for the research include but are not limited to population variability, susceptibility, developmental neurotoxicity, carcinogenicity, ecotoxicity, acute toxicity, etc. The outputs from this requirement will directly feed into the mission of the Department of Health & Human Services (HHS). This requirement would produce information to predict adverse human health effects from chemical exposures while also replacing, reducing, or refining the use of animals in toxicity testing. These services are necessary to support state of the art alternative toxicity testing at NIEHS. This acquisition is for continuing support services for alternative toxicological testing approaches that extend beyond the scope or capability of in-house staff. This acquisition will be competed as a 100% Set-Aside for Small Business concerns whereby only Small Business concerns will be eligible for award (size standard for associated NAICS is 1,000 employees). A small business concern, as defined by FAR 19.001, means any business entity organized for profit (even if its ownership is in the hands of a nonprofit entity) with a place of business located in the United States or its outlying areas and that makes a significant contribution to the U.S. economy through payment of taxes and/or use of American products, material and/or labor, etc. "Concern" includes but is not limited to an individual, partnership, corporation, joint venture, association, or cooperative. For more information, see 13 CFR 121.105. Additionally, for acquisitions conducted under a 100% Small Business Set-Aside, per FAR 19.505(b)(1)(i), Limitations on Subcontracting, the concern [small business prime contractor] will not pay more than 50 percent of the amount paid by the Government for contract performance to subcontractors that are not similarly situated entities [e.g. also small businesses]. Any work that a similarly situated entity further subcontracts will count towards the concern's 50 percent subcontract amount that cannot be exceeded. This acquisition represents a follow-on requirement to active contract HHSN273201500010C, with Integrated Laboratory Systems. The anticipated follow-on contract is anticipated to be a cost-plus fixed fee, term, level of effort contract with a base period of 12 months and nine successive 12-month term options for a total possible period of performance of 10 years (anticipated period of performance 6/1/2026 through 5/31/2036 if all term options are exercised). THE PENDING SOLICITATION WILL BE AVAILABLE ELECTRONICALLY ONLY. OFFERORS ARE RESPONSIBLE FOR ROUTINELY CHECKING THE SAM.GOV CONTRACT OPPORTUNITIES WEBSITE FOR ANY POSSIBLE SOLICITATION AMENDMENTS THAT MAY BE ISSUED. All responsible sources may submit a proposal, which shall be considered by the agency. This Pre-Solicitation notice does not commit the Government to award a contract(s). No collect calls or facsimile transmissions will be accepted. AGAIN, THIS IS A PRE-SOLICITATION ANNOUNCMENT ONLY AND NO RESPONSES ARE DUE AT THIS TIME.
Support for Evaluating and Conducting Computational and Alternative Toxicological Methods for the National Institute of Environmental Health Sciences is a federal acquisition solicitation issued by DEPARTMENT OF HEALTH AND HUMAN SERVICES. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.
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