Closed Solicitation · NATIONAL AERONAUTICS AND SPACE ADMINISTRATION

    TECHNOLOGY TRANSFER OPPORTUNITY: HUMAN TISSUE-LIKE CELLULAR ASSEMBLIES GROWN FOR RESPIRATORY STUDIES (MSC-TOPS-94)

    NATIONAL AERONAUTICS AND SPACE ADMINISTRATION
    Sol. T2P-JSC-00051Special NoticeWASHINGTON, DC
    Closed
    STATUS
    Closed
    closed Aug 13, 2025
    POSTED
    Sep 20, 2024
    Publication date
    NAICS CODE
    927110
    Primary industry classification
    PSC CODE
    9999
    Product & service classification

    AI Summary

    NASA is offering a technology transfer opportunity for companies interested in licensing the development of three-dimensional (3D) tissue-like assemblies (TLAs) of human broncho-epithelial (HBE) cells, which are designed for respiratory studies. This technology, developed at NASA Johnson Space Center, provides a more accurate in vitro model for researching human respiratory infections compared to traditional two-dimensional cell cultures. The 3D TLAs serve as a cost-effective alternative that mimics in vivo human tissue, facilitating studies on the effects of bioactive ingredients, vaccine development, and applications in the cosmetics and textile industries. Interested parties can apply

    Contract details

    Solicitation No.
    T2P-JSC-00051
    Notice Type
    Special Notice
    Posted Date
    September 20, 2024
    Response Deadline
    August 13, 2025
    NAICS Code
    927110AI guide
    PSC / Class Code
    9999
    Contract Code
    8000
    Issuing Office
    NASA HEADQUARTERS
    State
    DC
    ZIP Code
    20546
    AI Product/Service
    both

    Description

    NASA’s Technology Transfer Program solicits inquiries from companies interested in obtaining license rights to commercialize, manufacture and market the following technology. License rights may be issued on an exclusive or nonexclusive basis and may include specific fields of use. NASA provides no funding in conjunction with these potential licenses.

    THE TECHNOLOGY:

    Innovators at NASA Johnson Space Center have developed a technology that yields three-dimensional (3D) tissue-like assemblies (TLAs) of human broncho-epithelial (HBE) cells for in vitro research on infection of humans by respiratory viruses. Compared to traditional two-dimensional (2D) monolayer cell culture, the 3D TLAs more accurately represent the active environment present in respiratory infections. It offers a cost-effective platform that functions like in vivo human tissue, reducing the need for human subject testing and supporting a more controlled testing environment free from immune system limitations. 3D TLAs provide an opportunity to study the tolerance to bioactive ingredients, the impacts of developing vaccinations on respiratory tissues, and other applications directed to product development for the cosmetics and textile industries.

    To express interest in this opportunity, please submit a license application through NASA’s Automated Technology Licensing Application System (ATLAS) by visiting https://technology.nasa.gov/patent/MSC-TOPS-94

    If you have any questions, please e-mail NASA’s Technology Transfer Program at Agency-Patent-Licensing@mail.nasa.gov with the title of this Technology Transfer Opportunity as listed in this SAM.gov notice and your preferred contact information. For more information about licensing other NASA-developed technologies, please visit the NASA Technology Transfer Portal at https://technology.nasa.gov/

    These responses are provided to members of NASA’s Technology Transfer Program for the purpose of promoting public awareness of NASA-developed technology products, and conducting preliminary market research to determine public interest in and potential for future licensing opportunities. No follow-on procurement is expected to result from responses to this Notice.

    Key dates

    1. September 20, 2024Posted Date
    2. August 13, 2025Proposals / Responses Due

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    Frequently asked questions

    TECHNOLOGY TRANSFER OPPORTUNITY: HUMAN TISSUE-LIKE CELLULAR ASSEMBLIES GROWN FOR RESPIRATORY STUDIES (MSC-TOPS-94) is a federal acquisition solicitation issued by NATIONAL AERONAUTICS AND SPACE ADMINISTRATION. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.

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