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    Closed Solicitation · DEPT OF DEFENSE

    FUTURE PROGRAM: SMART-RED BLOOD CELLS (SMART-RBC)

    Issued by DEFENSE ADVANCED RESEARCH PROJECTS AGENCY · DEF ADVANCED RESEARCH PROJECTS AGCY
    Sol. DARPA-SN-25-107Special NoticeARLINGTON, VA
    Closed
    STATUS
    Closed
    closed Oct 31, 2025
    POSTED
    Sep 10, 2025
    Publication date
    NAICS CODE
    541714
    Primary industry classification
    PSC CODE
    AC12
    Product & service classification

    AI Summary

    The DARPA Smart-RBC program is seeking innovative research proposals to engineer red blood cells with novel biological features. This initiative aims to revolutionize blood products by developing smart red blood cells that can safely modify human physiology. Interested parties should prepare to engage in advanced biotechnology research.

    Contract details

    Solicitation No.
    DARPA-SN-25-107
    Notice Type
    Special Notice
    Posted Date
    September 10, 2025
    Response Deadline
    October 31, 2025
    NAICS Code
    541714AI guide
    PSC / Class Code
    AC12
    Issuing Office
    DEF ADVANCED RESEARCH PROJECTS AGCY
    Sub-Agency
    DEFENSE ADVANCED RESEARCH PROJECTS AGENCY
    Agency
    DEPT OF DEFENSE
    Primary Contact
    Dr. Christopher Bettinger, DARPA/BTO
    City
    ARLINGTON
    State
    VA
    ZIP Code
    222032114
    AI Product/Service
    service

    Description

    The purpose of this Special Notice (SN) is to provide public notification of additional research areas of interest to the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO), specifically for the forthcoming Smart-Red Blood Cells (Smart-RBC) program.

    The DARPA Smart-RBC program aims to engineer red blood cells to contain novel biological features that can safely and reliably modify human physiology. Specifically, the Smart-RBC program seeks to revolutionize blood products by creating “smart red blood cells” (SRBCs).

    Key dates

    1. September 10, 2025Posted Date
    2. October 31, 2025Proposals / Responses Due

    AI search tags

    biotechnology researchmedical researchbiological technologieshealthcare innovation

    Frequently asked questions

    FUTURE PROGRAM: SMART-RED BLOOD CELLS (SMART-RBC) is a federal acquisition solicitation issued by DEPT OF DEFENSE. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.

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