Closed Solicitation · DEPT OF DEFENSE
AI Summary
The Defense Advanced Research Projects Agency (DARPA) is seeking innovative concepts for a protein complex that responds to optical signals to synthesize DNA or RNA in living cells. This solicitation focuses on achieving high-fidelity nucleic acid synthesis and will proceed through a two-stage process, starting with written abstracts leading to oral proposals.
The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative concepts to design a protein complex that can be expressed in vivo (i.e., in a living cell) and responds to optical signals to synthesize a corresponding DNA or RNA sequence. This technology should enable massless transfer of genetic information to cells expressing the protein complex via a template-free mechanism that incorporates nucleotide bases in response to specific optical signals (e.g., different wavelengths of light). The GO program is focused on two main Research Objectives (ROs): (1) achieving the core capability of synthesizing DNA/RNA directly in living cells using optical signals, and (2) developing error mitigation methods that ensure high-fidelity nucleic acid synthesis. The acquisition process for GO will proceed through a two-stage process, starting with (1) written abstracts which will inform invitations to brief (2) an Oral Proposal Package (OPP) at DARPA.
GENERATIVE OPTOGENETICS (GO) is a federal acquisition solicitation issued by DEPT OF DEFENSE. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.
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