Closed Solicitation · DEPARTMENT OF HEALTH AND HUMAN SERVICES

    TOXICITY EVALUATION OF YC1 IN HSULT1A1 AND MSULT1A1 MICE

    Sol. 75N95025Q00237PresolicitationBethesda, MD
    Closed
    STATUS
    Closed
    closed Aug 18, 2025
    POSTED
    Aug 12, 2025
    Publication date
    NAICS CODE
    541380
    Primary industry classification
    PSC CODE
    B504
    Product & service classification

    AI Summary

    The National Institutes of Health is seeking proposals for a toxicity evaluation of YC1 in mice with humanized SULT1A1 and wild type SULT1A1. This research aims to establish the therapeutic window for YC1, which targets cancer cells expressing SULT1A1. Interested parties should prepare for a head-to-head comparison study.

    Contract details

    Solicitation No.
    75N95025Q00237
    Notice Type
    Presolicitation
    Posted Date
    August 12, 2025
    Response Deadline
    August 18, 2025
    NAICS Code
    541380AI guide
    PSC / Class Code
    B504
    Primary Contact
    Andrew Varley
    State
    MD
    ZIP Code
    20892
    AI Product/Service
    service

    Description

    NCATS seeks to determine if YC1 which works with a unique mechanism of cytotoxicity
    towards cancer cells that express SULT1A1. In doing so, NCATS shall establish the
    therapeutic window for YC1. To that end NCATS requires head-to-head comparison on
    YC1 in mice that have humanized SULT1A1 (custom mice available at
    GemPharmaTech) and with mouse SULT1A1 (wild type).

    Key dates

    1. August 12, 2025Posted Date
    2. August 18, 2025Proposals / Responses Due

    AI search tags

    Frequently asked questions

    TOXICITY EVALUATION OF YC1 IN HSULT1A1 AND MSULT1A1 MICE is a federal acquisition solicitation issued by DEPARTMENT OF HEALTH AND HUMAN SERVICES. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.

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