Active Solicitation · DEPT OF DEFENSE
AI Summary
The Defense Advanced Research Projects Agency (DARPA) is seeking innovative proposals for the Virtual-Integrated Twin for Autonomous Lifesaving (VITAL) program. This initiative aims to develop digital twin models of the cardiovascular system to enhance predictive decision-making in medical interventions. Proposals must address the integration of patient data and biological physics for real-time simulations and outcomes prediction.
UPDATE: The purpose of Amendment 1 to DARPA-PS-26-26, the Virtual-Integrated Twin for Autonomous Lifesaving (VITAL) Program Solicitation (PS), is to clarify the proposal abstract questions deadline and the 7-page proposal abstract section requirements. The Defense Advanced Research Projects Agency (DARPA) is soliciting innovative approaches to address challenges in developing continuously updating digital twin models of the cardiovascular system that combine patient data with biological physics to simulate in real time possible interventions and to predict their outcomes before actual intervention on a patient. The VITAL program will establish a foundation for causal, prediction-driven decision support in medicine, enabling clinicians and future autonomous systems to evaluate treatment options before they are applied. By defining when mechanistic digital twins, reduced-order models, and data-driven inference are reliable and actionable, VITAL will shift medical care from reactive assessment to anticipatory intervention. This capability has the potential to improve outcomes across acute, chronic, and emergent clinical settings.
Virtual-Integrated Twin for Autonomous Lifesaving (VITAL) is a federal acquisition solicitation issued by DEPT OF DEFENSE. Review the full description, attachments, and submission requirements on SamSearch before the response deadline.
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